PARS-HYNIC-BOMBESIN

KIT FOR THE PREPARATION OF PENTEATE (Sn) 99mTc-BOMBESIN INJECTION

Application

After labeling with Tc-99m, this peptide radiopharmaceutical kit is used as a diagnostic agent (mainly for location detection, staging, and follow-up of breast tumor treatment and programs).

This kit also has a special application in differentiating malignant tumors from benign breast tumors.

Gastrin-releasing peptide receptor (GRP) is a type of receptor in a variety of common human tumors, and radioactive Bombesin analogues show a high binding affinity for these receptors.

Preparation
  •  Add 0.5 mL 0.9% saline in an evacuated vial, and allow the mixture to preincubate for 5 min.
  •  Add aseptically sterile and non-pyrogenic solution of 99mTcO4 (10 – 40 mCi) in 0.5 mL saline.
  •  Shake the contents of the vial slowly for a few seconds.
  •  Heat the vial for 10 minutes at 95 °C.
  •  Wait 10 minutes for cooling to room temperature.
  • The reconstituted solution is stable for 6 hrs.
Storage
  •  Store the kit      – 20 °C, keep away from light and humidity
  • Store the reconstituted kit          15 – 25 °C

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