HYNIC-TATE
HYNIC-TATE

PARS-HYNIC-TATE

KIT FOR THE PREPARATION OF 99mTc-TYROSINE-OCTREOTATE INJECTION

Application

This radiopharmaceutical kit is used after labeling with Tc-99m as a diagnostic agent for localization, staging and treatment follow-up of neuroendocrine tumors.

Octreotate is a peptide (a small protein) which binds to somatostatin receptors on the cell surface of certain cancers, known collectively as neuroendocrine tumors.

Preparation
  •  Add 0.5 mL 0.9% saline in an evacuated vial, and allow the mixture to preincubate for 5 min.
  •  Add aseptically sterile and non-pyrogenic solution of 99mTcO4 (10 – 40 mCi) in 0.5 mL saline.
  • Shake the contents of the vial slowly for a few seconds.
  • Heat the vial for 10 minutes at 95 °C.
  • Wait 10 minutes for cooling to room temperature.
  • The reconstituted solution is stable for 6 hrs.
Storage
  • Store the kit        – 20 °C, keep away    from light and humidity
  • Store the reconstituted kit             15 – 25 °C

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