PARS-DTPA

KIT FOR THE PREPARATION OF PENTEATE (Sn) Tc-99m INJECTION

Application

DTPA (Diethylene-triamine-pentaacetate) as a radiopharmaceutical kit, after being labeled with Tc-99m, is used in renal imaging and primarily used to measure the glomerular filtration rate (GFR).

Other applications of Tc-99m DTPA include blood flow studies (brain, heart, extremities), cerebrospinal fluid circulation studies, studies of transport in the

gastrointestinal tract with labelled drinks and foods.

Preparation
  •  Injection sterile 99mTc (up to 300 mCi) aseptically into the vial in a volume of 2-5 mL
  •  Dissolve the lyophilized material by shaking the vial for 10 seconds and wait for 15 minutes.
  •  Examine the radiochemical purity (RCP).
  •  Labelled preparation is to be used within 6 hrs. Within this period the total RCP of 99mTc-DTPA should be more than 95.0%.
Storage
  •  Store the kit at            2 – 8 °C and protect from light
  •  Store the reconstituted kit  at         15 – 25 °C

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