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PARS‑MAA® Kit

 Sterile, NonPyrogen Lyophilized Powder

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KIT FOR THE PREPARATION OF AN INJECTABLE SUSPENSION OF HUMAN SERUM ALBUMIN MACROAGGRIGATES (Sn) 99mTc
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SPECT Imaging
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Diagnostic
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About the Product

PARS‑MAA is a sterile, non‑pyrogen lyophilized radiopharmaceutical kit for the diagnosis of lung diseases, which, after radiolabeling with Tc‑99m, is used for evaluation of these conditions via SPECT imaging. The MAA kit is intended solely for diagnostic use and for the preparation of 99mTc‑MAA.

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Applications
  • Evaluation of pulmonary function (lung perfusion scan)
  • Diagnosis of pulmonary embolism and myocardial infarction
  • Assessment of chronic circulatory failure
  • Diagnosis of regional respiratory distress
  • Diagnosis of emphysema, tumors, and various inflammatory conditions
  • Venous blood flow scan
  • Blood perfusion scan in abdominal and posterior organs
  • Diagnosis of deep vein thrombosis in the lower extremities and pelvis
  • Assessment of possible inferior vena cava obstruction
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Mechanism of Action

In 99mTc‑MAA, the particle size typically ranges from 10 to 90 micrometers. When a suspension of radiolabeled particles is injected intravenously, most particles become trapped upon passing through the first capillary bed of the pulmonary circulation and are cleared from the bloodstream. This allows for imaging of the lungs.

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Preparation and Administration

Note: This pharmaceutical product is intended solely for use in nuclear medicine facilities by personnel experienced in handling radiopharmaceuticals.

The PARS‑MAA® kit is manufactured under aseptic conditions. After radiolabeling with a specified amount of sterile, non‑pyrogen sodium pertechnetate injection (Na99mTcO₄) — eluted from a 99Mo/99mTc generator — the preparation is ready for intravenous administration. The dose to be used will be prescribed by the physician.

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Box Contents

Each box contains one instruction leaflet and five MAA kit vials, along with five labels specifically for the radiolabeling procedure.

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Composition

Human Serum Albumin Macroaggregated (5 mg)

Stannous Chloride Dihydrate

Tween 80

Sodium Acetate

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Storage Conditions
  • Store the PARS‑MAA® kit in a refrigerator (2°C to 8°C) and protected from light. The cold chain must be maintained under all circumstances.
  • After radiolabeling, 99mTc‑MAA remains stable for up to 6 hours at 15°C to 25°
  • The PARS‑MAA® kit should not be used after the expiration date.
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