SULFURCOLLOID
SULFURCOLLOID

PARS-SULFURCOLLOID

KIT FOR THE PREPARATION OF 99mTc SULFURCOLLOID INJECTION

Application

After labeling with Tc-99m, this radiopharmaceutical kit is mainly used as a diagnostic agent to provide liver and spleen scans.

Tc-99m-sulfurcolloid as a diagnostic radiopharmaceutical agent is used for diagnosis of parenchymal liver diseases and studies of hepatic space-occupying lesions (such as metastases).

Other applications of this radiopharmaceutical are as follows:

  • Lymphoscintigraphy
    • encircling the lesion site for a melanoma study
    • in the webs of the fingers and toes for a lymphatic mapping study
  • Stomach emptying scan
  • Gastrointestinal tract bleeding
  • Evaluation of various conditions including lymph node metastases in breast cancer
  • Imaging of reticuloendothelial cells to evaluate liver function
  • Esophageal and gastrointestinal transit studies
Preparation

(All steps should be in aseptic condition)

  • Add 0.1 ml of hydrochloric acid solution (2-a) to the reaction vial.
  • Add 10-100 mCi of freshly pertechnetate (99mTcO4) in 1-2 ml to the  reaction vial.
  • Heat 30 min in boiling water bath.
  • Cool, add 1.3 ml of phosphate buffer solution (2-b) to reaction vial.
  • The reconstituted solution is stable for 4 hrs.
  •  Stability of 99mTc – Sulfurcolloid                          4 h
Storage
  •  Store the kit at            2 – 8 °C
  •  Store the reconstituted kit  at         15 – 25 °C

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